Whole body washing enables a clean procedure

Antimicrobial skin cleanser HiBiScrub® contains chlorhexidine gluconate, which unlike soaps and gels, binds to the skin and offers persistent, superior protection for six hours2. The efficacy is strengthened upon repeated application3. HiBiScrub containing the active chlorhexidine gluconate has a significant proven efficacy killing a wide range of Gram-negative and Gram-positive bacteria, yeasts, fungi and viruses4. Helping to provide protection against surgical site infections and incision site bacterial growth of microorganisms in less than 60 seconds5. This helps to provide protection against surgical site infections6.


Using a nasal antibiotic in conjunction with whole body washing with HiBiScrub reduces the risk of S aureus associated HAIs by nearly 60%7

Helps provide protection against surgical site infections (SSIs) and hospital acquired infections (HAIs)6

Provides instant protection8

Provides residual protection, up to 6 hours long-lasting effect2

Kills a wide range of microorganisms4, 5

Is kind to skin9, even with frequent use10

HiBiScrub improves cost effectiveness by helping to provide protection against surgical site infections



A recent study from the European Commission shows that an additional 16 million extra hospital days were attributed to treating HAIs at a cost of EUR 435 daily, resulting in additional spend of EUR 7 billion per year12. Implementing a whole body wash procedure can reduce the number of HAIs and therefore unnecessary costs associated with treatment.

Whole body washing

Incorporate whole body washing in infection control guidelines

Incorporating whole body washing into infection control guidelines can influence surgical procedures to be genuinely clean from the very start. Using HiBi high quality antiseptic products to prepare patients before and after surgery will help to provide protection against SSIs. HiBiScrub for whole body washing is a highly effective antiseptic solution.

HiBiScrub will keep working long after application, continuously killing bacteria for up to six hours2. This will reduce the natural bacteria found on one in three people’s skin12 by 94%13.

Clinical research on whole body washing

The patient is a source of contamination due to the significant relationship between positive skin culture and wound infection rates14.

A randomized controlled trial published in the New England Journal of Medicine shows that whole body washing with HiBiScrub in conjunction with mupirocin nasal ointment can reduce S aureus associated hospital acquired infections by up to 60%5.

Each year in the EU, one in every 20 patients acquires a hospital acquired infection (HAI), leading to 4.5 million infections15. According to the Centers for Disease Control (CDC) 2-5% of patients undergoing surgery will acquire a surgical site infection (SSI)12.

Ref. No. 

HiBi Scrub prescribing information
Trade name: HiBi Scrub
Qualitative and quantitative composition: Chlorhexidine Gluconate 4.0% w/v (incorporated as Chlorhexidine Gluconate Solution Ph. Eur.)
Pharmaceutical form: Liquid
Clinical particulars:

Therapeutic indications

Hibiscrub is an antimicrobial preparation for pre-operative surgical hand disinfection, antiseptic handwashing on the ward and pre-operative and post-operative skin antisepsis for patients undergoing elective surgery.

Posology and method of administration

For external use only

Pre-operative surgical hand disinfection

Wet the hands and forearms, apply 5ml of Hibiscrub and wash for one minute cleaning the fingernails

with a brush or scraper. Rinse, apply a further 5ml of Hibiscrub and continue washing for a further 2 minutes. Rinse thoroughly and dry.

Antiseptic handwash on the ward

Wet the hands and forearms, apply 5ml of Hibiscrub and wash for 1 minute. Rinse thoroughly and dry.

Pre-operative skin antisepsis for the patient

The patient washes his whole body in the bath or shower on at least 2 occasions, usually the day before and the day of operation as follows:

The day before operation the patient washes with 25ml of Hibiscrub beginning with the face and working downwards paying particular attention to areas around the nose, axillae, umbilicus, groin and perineum. The body is then rinsed and the wash repeated with a further 25ml, this time including the hair. Finally the patient rinses his entire body thoroughly and dries on a clean towel. This procedure should be repeated the following day. Patients confined to bed can be washed with Hibiscrub using a standard bed-bath technique.

Conventional disinfection of the operation site will then be performed when the patient is in theatre.

Post-operative skin antisepsis for the patients

The patient washes his whole body, excluding the operation wound, in the bath or shower usually onthe third day after operation using the procedure described above.

Contraindications, warnings etc.


Known hypersensitivity to the product or any of its components, especially in those with a history of possible chlorhexidine-related allergic reactions.

Special warnings and precautions for use:

Hibiscrub contains chlorhexidine. Chlorhexidine is known to induce hypersensitivity, including generalised allergic reactions and anaphylactic shock. The prevalence of chlorhexidine hypersensitivity is not known, but available literature suggests this is likely to be very rare. Hibiscrub should not be administered to anyone with a potential history of an allergic reaction to a chlorhexidine-containing compound.

For external use only. Keep out of the eyes and avoid contact with the brain, meninges and middle ear. In patients with head or spinal injuries or perforated ear drum, the benefit of use in pre-operative preparation should be evaluated against the risk of contact. If chlorhexidine solutions come into contact with the eyes, wash out promptly and thoroughly with water. Do not inject or use in body cavities.

Interaction with other medicaments and other forms of interaction:

Chlorhexidine is incompatible with soap and other anionic agents. Hypochlorite bleaches may cause brown stains to develop in fabrics, which have previously been in contact with preparations containing chlorhexidine.

Use in pregnancy and lactation:

There is no evidence of any adverse effects on the foetus arising from the use of Hibiscrub as a handwash during pregnancy and lactation. Therefore no special precautions are recommended.

Shelf life: 36 months.
Special storage precautions: Do not store above 25ºC
Product licence holder: Regent Medical Overseas Ltd 
Product licence number: PL 21855/0002
Basic NHS Price: HiBiScrub 500ml: £5,25; HiBiScrub 250ml: £4.25
Information last updated: February 2013.

1. Mölnlycke Health Care Report REPR0145
2  JTanner et al. A fresh look at perioperative body washing. Journal of Infection Prevention. (2012) vol 13 11 - 15
3. Faogali J et al; 1995. Comparison of the immediate, residual, and cumulative antibacterial effects of Novaderm R, Novascrub R, Betadine Surgical Scrub, Hibiclens, and liquid soap. Vol 23; 337-343
4. Denton, GW; 2001. Chlorhexidine. Chapter 15 in Disinfection, Sterilization, and Preservation. Ed. Block SS. Fifth Ed. Lippincott Williams and Wilkins.
5. Mölnlycke Health Care Report REPR0432
6. Hayek et al, J Hosp Infect. 1987; 10:165-172
7. Bode LGM et al; 2010. NEJM. Preventing Surgical-Site infections in nasal carriers of Staphylococcus aureus. Vol 362; 9-17.  
8. Mölnlycke Health Care Report REPR0432
9. Mölnlycke Health Care Report REPR0781
10. Larson EL, Eke PI, Laughon BE. 1986. Efficacy of alcohol-based hand rinses under frequent use conditions. Antimicrobial Agents and Chemotherapy. Vol 30; 542-544
11. European Centre for Disease Prevention and Control. Annual epidemiological report on the communicable diseases in Europe 2008. Chapter 2: Healthcare-associated infections.
12. Health Protection Agency, MRSA information for patients (www.hpa.org.uk)
13. Bryne DJ, Napier A, Cuschieri A. 1990. Rationalizing whole body disinfection J Hosp Infect. 15(2):183-7.
14. Brote L. 1976. wound infections in clean an potentially contaminated surgery. Acta Chir Scand. 142: 191-200
15 Commission of the European Communities. Accompanying document to the Communication and Recommendation on patient safety, including the prevention and control of healthcare associated infections. December 2008.
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